Widely used in surfactant systems (cleansers, body wash, shampoo) and in emulsions (creams/lotions). Easy to add to the aqueous phase and remains effective over a wide pH range. Because it is a formaldehyde-releasing preservative, it is best to formulate at the lowest effective dose and include a chelating agent (e.g., disodium EDTA).

Benefits:

●       Broad-spectrum protection against bacteria, yeast, and mold

●       Water-soluble and easy to incorporate

●       Effective across an approximate pH range of 3–9

●       Suitable for both rinse-off and leave-on products

●       Good compatibility with anionic, nonionic, and amphoteric systems

●       Can be boosted with co-preservatives when needed

How to use:

●       Add to the aqueous phase or during cool-down (≤ 45–50 °C) with moderate stirring.

●       Typical working pH range: 3–9 (optimal around 5–8).

●       Use the lowest level that achieves efficacy and perform microbiological challenge testing.

●       Avoid excessive heat/prolonged heating to minimize loss of activity.

●       Comply with labeling requirements for formaldehyde releasers and applicable limits; patch testing is advisable for sensitive skin.

Recommended usage levels in skincare:

●       Leave-on creams/lotions/serums: 0.1–0.4%

●       Rinse-off cleansers, body wash, shampoo: 0.2–0.6%

Solubility:

●       Soluble in water, alcohol, and many glycols

●       Insoluble in oils and non-polar solvents

Applications:

●       Facial and body cleansers; shower gels

●       Shampoos and scalp cleansers

●       Face and body creams and lotions

●       Hand and foot care creams

●       Makeup removers with an appropriate preservation system

Storage:
 Keep tightly closed, protected from light and moisture, at a moderate temperature (below 25 °C). Ensure adequate ventilation for large containers and avoid prolonged heat exposure.